Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Lappeenrannan-Lahden teknillinen yliopisto LUT

Lappeenranta-Lahti University of Technology LUT intends to make a purchase of Liquid chromatography-tandem mass spectrometry.

Määräaika

Tarjousten vastaanottamisen määräaika oli 2019-11-13. Hankinta julkaistiin 2019-10-11.

Kuka?

• Lappeenrannan-Lahden teknillinen yliopisto LUT

Mitä?

• Laboratoriolaitteet, optiset ja tarkkuuslaitteet (lukuun ottamatta silmälaseja)

Missä?

• Etelä-Suomi › Etelä-Karjala

Hankintojen historia

Päivämäärä	Asiakirja
2019-10-11	hankintailmoitus
2020-01-29	Ilmoitus tehdystä sopimuksesta

hankintailmoitus (2019-10-11)
Kohde
Hankinnan laajuus
Otsikko: Laboratoriolaitteet, optiset ja tarkkuuslaitteet (lukuun ottamatta silmälaseja)
Lyhyt kuvaus:

Lappeenranta-Lahti University of Technology LUT intends to make a purchase of Liquid chromatography-tandem mass spectrometry.

Ilmoituksen metatiedot
Alkukieli: englanti 🗣️
Asiakirjatyyppi: hankintailmoitus
Sopimuksen luonne: Tavarat
Asetus: Euroopan unioni ja WTO-maat
Yhteinen hankintanimikkeistö (CPV)
Koodi: Laboratoriolaitteet, optiset ja tarkkuuslaitteet (lukuun ottamatta silmälaseja) 📦
Suorituspaikka
NUTS-alue: Etelä-Karjala 🏙️

Menettely
Menettelyn tyyppi: Avoin menettely
Tarjouksen tyyppi: Tarjous koskee kaikkia eriä
Myöntämisperusteet
Kokonaistaloudellisesti edullisin tarjous

Hankintaviranomainen
Tunnistetiedot
Maa: Suomi 🇫🇮
Hankintaviranomaisen tyyppi: Muu
Hankintaviranomaisen nimi: Lappeenrannan-Lahden teknillinen yliopisto LUT
Postiosoite: Yliopistonkatu 34
Postinumero: 53850
Postitoimipaikka: Lappeenranta
Yhteystiedot
Internetosoite: http://www.lut.fi 🌏
Sähköposti: hankinnat@lut.fi 📧
Puhelin: +358 294462111 📞
Asiakirjojen URL-osoite: https://hanki.tarjouspalvelu.fi/hanki 🌏
Osallistumisen URL-osoite: https://tarjouspalvelu.fi/hanki?id=256640&tpk=c5aa03d8-e854-43fd-85f1-8f0a0edcee24 🌏

Viite
Päivämäärät
Lähetyspäivä: 2019-10-11 📅
Tarjousten jättämisen määräaika: 2019-11-13 📅
Julkaisupäivä: 2019-10-15 📅
Tunnisteet
Ilmoituksen numero: 2019/S 199-482990
EUVL-S-numero: 199

Kohde
Hankinnan laajuus
Arvioitu kokonaisarvo: 220 000 EUR 💰
Lyhyt kuvaus:

Background Liquid chromatography-tandem mass spectrometry (LC-MS/MS): this equipment is one of the most valuable and powerful analytical instruments applied in a wide range of areas including environmental monitoring, and analysis, pharmaceutical, food processing, agrochemical and cosmetic industries. Recently, environmental monitoring and impact assessment associated with various contaminants including low or non-volatile organic compounds in an aqueous solution cannot be handled with high-pressure liquid chromatography (HPLC) or gas chromatography. LC-MS/MS is an instrument that combines liquid chromatography (LC or HPLC) with mass spec-trometry (MS). Coupled with MS is popular in chemical analysis due to the enhanced specificity and selectivity by two MS analyzers (i.e., triple quadrupole). The increased sensitivity using LC-MS/MS is also achieved to reach low parts per billion (ppb). Among the ionization techniques, electrospray ionization (ESI) allows the production of multiply charged ion which results in the ability of analyzing high molecular weight species. ESI also allows sensitive detection of singly charged low molecular weight polar species such as drugs and drug metabolites. The formation of positive or negative ions occurs in high yield. Additionally, ESI is an atmospheric pressure process, which makes it easy to use and easy to interface with HPLC and capillary electrophoresis (CE) separation techniques. In the proposed application, ultra-high-performance liquid chromatography (UHPLC) coupled with triple quadrupole mass analyzer will be purchased for separation and simultaneous quantification of analytes in environmental samples and fast switching between positive and negative ion modes will be an asset. Scan, SIM, and MRM mode will be acquired as MS and MS/MS acquisition mode for further targeting and searching for precursor and product ions of analytes.

Description of current state:

The current existing equipment in the Department of Green Chemistry, LUT is HPLC, which delivers a less sensitive and has limitation to structural identification of the individual component in water samples. Due to the detection limit of current equipment, it is not possible to determine the ppb level concentration of emerging pollutants. To improve structural identification and detection sensitivity, an alternative instrument that currently present at DGC is gas chromatography-mass spectrometry (GC-MS). However, multiple manual sample preparation steps including pre-concentration of water samples prior to analysis are required, which result in decreased reproducibility, accuracy and sensitivity the analytical methodology throughout. Additionally, a large initial volume of sample is essential. At DGC and other LUT research entities, researchers have frequent and extensive analysis of water samples for environmental monitoring and analysis, and evaluation of materials and technology for water purification and environmental applications. Increasingly, researchers are being challenged to understand trace non-volatile organic contaminants as well as to identify intermediates or by-products in their research activities, but they lack a key analytical tool. Specifically, the incorporation of LC-MS/MS within DGC will enhance the research teams’ ability. This will enable LUT’s researchers to effectively compete with researchers from other universities around the world by analyzing and monitoring their samples with the same level of detection, sensitivity and reliability. Description of the target state (which needs should be fulfilled). The proposed LC-MS/MS in this application is an atmospheric pressure ionization or electrospray ionization (ESI) triple quadrupole LC-MS/MS complete with thermostated autosampler, binary pressure gradient pumps, column oven, computer, nitrogen gas generator, rotary pump, soft-ware, installation, and training. A full description of the procurement is Appendix 1.

Arvioitu arvo ilman arvonlisäveroa: 220 000 EUR 💰
Kesto: 24 kuukautta
Uudistusten kuvaus: The agreement is valid until the end of the warranty period.
Vaihtoehtojen kuvaus: Reserve the possibility to order additional products.

Menettely
Oikeusperusta: 32014L0024
Tarjousten vastaanottoaika: 12:00
Kielet, joilla tarjoukset tai osallistumishakemukset voidaan jättää: englanti 🗣️
suomi 🗣️
Tarjouksen voimassaoloaika: 3 kuukautta
Tarjousten avauspäivä: 2019-11-13 📅
Tarjousten avausaika: 14:00

Hankintaviranomainen
Tunnistetiedot
Kansallinen rekisterinumero: 0245904-2
Muu hankintaviranomaisen tyyppi: University
Yhteystiedot
Asiakirjojen URL-osoite: https://hanki.tarjouspalvelu.fi/hanki 🌏

Täydentävät tiedot
Arvostelurunko
Nimi: Markkinaoikeus
Postiosoite: Radanrakentajantie 5
Postitoimipaikka: Helsinki
Postinumero: 00520
Maa: Suomi 🇫🇮
Puhelin: +358 295643300 📞
Sähköposti: markkinaoikeus@oikeus.fi 📧
Faksi: +358 295643314 📠
Internetosoite: http://www.oikeus.fi/markkinaoikeus 🌏
Lähde: OJS 2019/S 199-482990 (2019-10-11)

Ilmoitus tehdystä sopimuksesta (2020-01-29)
Kohde
Hankinnan laajuus
Lyhyt kuvaus:

Lappeenranta-Lahti University of Technology LUT intends to make a purchase of liquid chromatography-tandem mass spectrometry.

Ilmoituksen metatiedot
Asiakirjatyyppi: Ilmoitus tehdystä sopimuksesta

Menettely
Tarjouksen tyyppi: Ei sovelleta

Viite
Päivämäärät
Lähetyspäivä: 2020-01-29 📅
Julkaisupäivä: 2020-01-31 📅
Tunnisteet
Ilmoituksen numero: 2020/S 022-047998
Viittaa ilmoitukseen: 2019/S 199-482990
EUVL-S-numero: 22

Kohde
Hankinnan laajuus
Lyhyt kuvaus:

Background

Liquid chromatography-tandem mass spectrometry (LC-MS/MS): This equipment is one of the most valuable and powerful analytical instruments applied in a wide range of areas including environmental monitoring, and analysis, pharmaceutical, food processing, agrochemical and cosmetic industries. Recently, environmental monitoring and impact assessment associated with various contaminants including low or non-volatile organic compounds in an aqueous solution cannot be handled with high-pressure liquid chromatography (HPLC) or gas chromatography.

LC-MS/MS is an instrument that combines liquid chromatography (LC or HPLC) with mass spectrometry (MS). Coupled with MS is popular in chemical analysis due to the enhanced specificity and selectivity by two MS analyzers (i.e., triple quadrupole). The increased sensitivity using LC-MS/MS is also achieved to reach low parts per billion (ppb). Among the ionization techniques, electrospray ionization (ESI) allows the production of multiply charged ion which results in the ability of analyzing high molecular weight species. ESI also allows sensitive detection of singly charged low molecular weight polar species such as drugs and drug metabolites. The formation of positive or negative ions occurs in high yield. Additionally, ESI is an atmospheric pressure process, which makes it easy to use and easy to interface with HPLC and capillary electrophoresis (CE) separation techniques.

In the proposed application, ultra-high-performance liquid chromatography (UHPLC) coupled with triple quadrupole mass analyzer will be purchased for separation and simultaneous quantification of analytes in environmental samples, and fast switching between positive and negative ion modes will be an asset. Scan, SIM, and MRM mode will be acquired as MS and MS/MS acquisition mode for further targeting and searching for precursor and product ions of analytes.

Description of current state

The current existing equipment in the Department of Green Chemistry, LUT is HPLC, which de-livers a less sensitive and has limitation to structural identification of the individual component in water samples. Due to the detection limit of current equipment, it is not possible to determine the ppb level concentration of emerging pollutants. To improve structural identification and detection sensitivity, an alternative instrument that currently present at DGC is gas chromatography-mass spectrometry (GC-MS). However, multiple manual sample preparation steps including pre-concentration of water samples prior to analysis are required, which result in decreased reproducibility, accuracy and sensitivity the analytical methodology throughout. Additionally, a large initial volume of sample is essential.

At DGC and other LUT research entities, researchers have frequent and extensive analysis of water samples for environmental monitoring and analysis, and evaluation of materials and technology for water purification and environmental applications. Increasingly, researchers are being challenged to understand trace non-volatile organic contaminants as well as to identify intermediates or by-products in their research activities, but they lack a key analytical tool. Specifically, the incorporation of LC-MS/MS within DGC will enhance the research teams’ ability. This will en-able LUT’s researchers to effectively compete with researchers from other universities around the world by analyzing and monitoring their samples with the same level of detection, sensitivity, and reliability.

Description of the target state (which needs should be fulfilled)

The proposed LC-MS/MS in this application is an atmospheric pressure ionization or electrospray ionization (ESI) triple quadrupole LC-MS/MS complete with thermostated autosampler, binary pressure gradient pumps, column oven, computer, nitrogen gas generator, rotary pump, soft-ware, installation, and training.

A full description of the procurement is Appendix 1.

Menettely
Myöntämisperusteet
Laatukriteeri (nimi): Quality
Laatukriteeri (painotus): 45
Hinta (painotus): 55
Lähde: OJS 2020/S 022-047998 (2020-01-29)

Uudet hankinnat asiaan liittyvissä luokissa 🆕

Laboratoriolaitteet, optiset ja tarkkuuslaitteet (lukuun ottamatta silmälaseja) (19 uudet hankinnat)